Peptides for Fix Your Gut
Heal your gut, heal everything
Gut health affects your energy, your skin, your immune system — basically everything. BPC-157 is the most talked-about peptide for gut healing, though it is still in early research. Teduglutide is an FDA-approved option for serious gut conditions.
Your options at a glance
How are these accessed?
Peptides for this goal come through different routes depending on their approval status:
Doctor’s prescription — FDA-approved peptides prescribed like any medication and filled at a regular pharmacy.
Compounding pharmacy — Doctor writes a prescription to a licensed compounding pharmacy. HHS restored Category 1 compounding eligibility for many peptides in February 2026.
Research only — Available through research vendors but not approved for human use. No quality guarantees.
Safe, established options
These are FDA-approved and prescribed by doctors every day.
Helps the intestine absorb more nutrients by promoting gut lining growth. Used for short bowel syndrome.
Teduglutide
Gattex
Still in early research
Interesting science, but not yet proven in humans. Consult your doctor before exploring these.
Widely discussed for tissue repair and gut healing, but NOT FDA-approved. Human evidence is extremely limited despite popular claims.
BPC-157
Heads up: FDA has flagged safety concerns with this one.
Read the full guide →A powerful anti-inflammatory tripeptide that shows promise for gut inflammation and skin conditions. Often used in combination with BPC-157 for gut healing protocols. Still early-stage research.
KPV
A naturally occurring neuropeptide that connects your gut and brain. Being explored for gut healing, circadian rhythm regulation, and jet lag recovery. Early research but growing interest in the wellness community.
VIP
The leading peptide candidate for "leaky gut" — it works by tightening the junctions between gut cells. Currently in Phase 3 clinical trials for celiac disease, which is further along than most peptides on this list.
Larazotide
A peptide that acts on the innate repair receptor — it helps your body reduce inflammation and repair tissue without suppressing your immune system. Being studied for neuropathy, gut health, and metabolic regulation.
ARA290
Ready to explore? Here’s how to do it safely.
Learn first
You’re already doing this! Read through the guides above to understand what each peptide does.
Discuss with your doctor
Share what you’ve learned with your own healthcare provider to discuss whether any options might be right for you.
Start the conversation
Bring what you’ve learned here. A good doctor will appreciate that you’ve done your homework.